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FcγRIIIa Signaling Modulates Endosomal Toll-Like Receptors Responses in Human CD4(+) T-cells
Recognition of antibody-opsonized pathogens by immune cells triggers both toll-like receptor (TLR) and Fc-receptor (FcR) signaling. FcRs endocytose modified nucleic acids bound to antibodies and deliver them to endosomes, where they are recognized by nucleic acid-sensing TLRs (NA-TLRs). We show that...
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| Опубликовано в: : | J Immunol |
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| Главный автор: | |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5505339/ https://ncbi.nlm.nih.gov/pubmed/28500073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1601954 |
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