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FcγRIIIa-Syk Co-signal Modulates CD4(+) T-cell Response and Up-regulates Toll-like Receptor (TLR) Expression
CD4(+) T-cells in systemic lupus erythematosus (SLE) patients show altered T-cell receptor signaling, which utilizes Fc-receptor γ-chain FcRγ-Syk. A role for FcγRIIIa activation from immune complex (IC) ligation and sublytic terminal complement complex (C5b-9) in CD4(+) T-cell responses is not inves...
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| Publicat a: | J Biol Chem |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4714221/ https://ncbi.nlm.nih.gov/pubmed/26582197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.684795 |
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