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Gradual Increase of FcγRIIIa/CD16a Expression and Shift toward IFN-γ Secretion during Differentiation of CD56(dim) Natural Killer Cells

Natural killer (NK) cell effector functions include cytotoxicity and secretion of cytokines such as interferon-γ (IFN-γ). The immature CD56(bright) subset of human NK cells lacks expression of FcγRIIIa/CD16a, one of the low-affinity immunoglobulin G receptors, or exhibits low-density expression (CD5...

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Udgivet i:Front Immunol
Main Authors: Lajoie, Laurie, Congy-Jolivet, Nicolas, Bolzec, Armelle, Thibault, Gilles
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701929/
https://ncbi.nlm.nih.gov/pubmed/29209315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01556
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