Selective Antibody Intervention of Toll-like Receptor 4 Activation through Fc γ Receptor Tethering

Inflammation is mediated mainly by leukocytes that express both Toll-like receptor 4 (TLR4) and Fc γ receptors (FcγR). Dysregulated activation of leukocytes via exogenous and endogenous ligands of TLR4 results in a large number of inflammatory disorders that underlie a variety of human diseases. Thu...

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Autori principali: Shang, Limin, Daubeuf, Bruno, Triantafilou, Martha, Olden, Robin, Dépis, Fabien, Raby, Anne-Catherine, Herren, Suzanne, Dos Santos, Anaelle, Malinge, Pauline, Dunn-Siegrist, Irene, Benmkaddem, Sanae, Geinoz, Antoine, Magistrelli, Giovanni, Rousseau, François, Buatois, Vanessa, Salgado-Pires, Susana, Reith, Walter, Monteiro, Renato, Pugin, Jérôme, Leger, Olivier, Ferlin, Walter, Kosco-Vilbois, Marie, Triantafilou, Kathy, Elson, Greg
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140888/
https://ncbi.nlm.nih.gov/pubmed/24737331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.537936
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