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Characterization of a surrogate murine antibody to model anti-human CD3 therapies
Fc-modified anti-human CD3ε monoclonal antibodies (mAbs) are in clinical development for the treatment of autoimmune diseases. These next generation mAbs have completed clinical trials in patients with type-1 diabetes and inflammatory bowel disease demonstrating a narrow therapeutic window. Lowered...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3906309/ https://ncbi.nlm.nih.gov/pubmed/23751612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.24736 |
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