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A Mild and General Larock Indolization Protocol for the Preparation of Unnatural Tryptophans
A mild and general protocol for the Pd(0)-catalyzed heteroannulation of o-bromoanilines and alkynes is described. Application of a Pd(0)/P((t)Bu)(3) catalyst system enables the efficient coupling of o-bromoanilines at 60 °C, mitigating deleterious side reactions and enabling access to a broad range...
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| Pubblicato in: | Org Lett |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5505074/ https://ncbi.nlm.nih.gov/pubmed/27598827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b02477 |
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