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A Copper-Catalyzed Arylation of Tryptamines for the Direct Synthesis of Aryl Pyrroloindolines

An operationally simple, copper-catalyzed arylation of N-tosyltryptamines provides direct access to C3-aryl pyrroloindolines. A range of electron-donating and electron-withdrawing substituents is tolerated on both the indole backbone and the aryl electrophile. These reactions occur under ambient tem...

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Bibliografiske detaljer
Main Authors: Kieffer, Madeleine E., Chuang, Kangway V., Reisman, Sarah E.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3480223/
https://ncbi.nlm.nih.gov/pubmed/23105962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C2SC20914D
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