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Application of Daugulis Copper-Catalyzed Direct Arylation to the Synthesis of 5-Aryl Benzotriazepines

[Image: see text] A method for the direct arylation of benzotriazepines is reported, employing an aryl iodide as the coupling partner, copper iodide as the catalyst, and lithium t-butoxide as the base. A variety of electron-rich, electron-poor, and sterically hindered aryl iodides are compatible wit...

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Autori principali: Yotphan, Sirilata, Bergman, Robert G., Ellman, Jonathan A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2674648/
https://ncbi.nlm.nih.gov/pubmed/19260648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol900103a
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