Antisense Oligonucleotides Reduce RNA Foci in Spinocerebellar Ataxia 36 Patient iPSCs

Spinocerebellar ataxia type 36 is a late-onset, slowly progressive cerebellar syndrome with motor neuron degeneration that is caused by expansions of a hexanucleotide repeat (GGCCTG) in the noncoding region of NOP56 gene, with a histopathological feature of RNA foci formation in postmortem tissues....

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Matsuzono, Kosuke, Imamura, Keiko, Murakami, Nagahisa, Tsukita, Kayoko, Yamamoto, Takuya, Izumi, Yuishin, Kaji, Ryuji, Ohta, Yasuyuki, Yamashita, Toru, Abe, Koji, Inoue, Haruhisa
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2017
Témata:
Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504081/
https://ncbi.nlm.nih.gov/pubmed/28918022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.06.017
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky