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Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle

The mechanistic target of rapamycin (mTOR) is a central mediator of protein synthesis in skeletal muscle. We utilized immunofluorescence approaches to study mTOR cellular distribution and protein-protein co-localisation in human skeletal muscle in the basal state as well as immediately, 1 and 3 h af...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Song, Zhe, Moore, Daniel R., Hodson, Nathan, Ward, Carl, Dent, Jessica R., O’Leary, Mary F., Shaw, Andrew M., Hamilton, D. Lee, Sarkar, Sovan, Gangloff, Yann-Gaël, Hornberger, Troy A., Spriet, Lawrence L., Heigenhauser, George J., Philp, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5504043/
https://ncbi.nlm.nih.gov/pubmed/28694500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05483-x
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