Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting

Complement protein C3 is the pivotal component of the complement system. Previous studies have demonstrated that C3 has implications in various human diseases and exerts profound functions under certain conditions. However, the delineation of pathological and physiological roles of C3 has been hampe...

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Publicado no:Sci Rep
Main Authors: Zhang, Wei, Wang, Guan, Wang, Ying, Jin, Yong, Zhao, Lihua, Xiong, Qiang, Zhang, Lining, Mou, Lisha, Li, Rongfeng, Yang, Haiyuan, Dai, Yifan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503937/
https://ncbi.nlm.nih.gov/pubmed/28694465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05400-2
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