Dickkopf-related protein 2 induces G0/G1 arrest and apoptosis through suppressing Wnt/β-catenin signaling and is frequently methylated in breast cancer

Dickkopf-related protein 2 (DKK2) is one of the antagonists of Wnt/β-catenin signaling, with its downregulation reported in multiple cancers. However, how DKK2 contributes to breast tumorigenesis remains unclear. We examined its expression and promoter methylation in 10 breast tumor cell lines, 98 p...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Mu, Junhao, Hui, Tianli, Shao, Bianfei, Li, Lili, Du, Zhenfang, Lu, Li, Ye, Lin, Li, Shuman, Li, Qianqian, Xiao, Qian, Qiu, Zhu, Zhang, Yan, Fan, Jiangxia, Ren, Guosheng, Tao, Qian, Xiang, Tingxiu
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2017
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503624/
https://ncbi.nlm.nih.gov/pubmed/28467796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17055
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