FBXW7 missense mutation: a novel negative prognostic factor in metastatic colorectal adenocarcinoma

BACKGROUND: FBXW7 functions as a ubiquitin ligase tagging multiple dominant oncogenic proteins and commonly mutates in colorectal cancer. Data suggest missense mutations lead to greater loss of FBXW7 function than other gene aberrations do. However, the clinicopathologic factors and outcomes associa...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Korphaisarn, Krittiya, Morris, Van Karlyle, Overman, Michael J., Fogelman, David R., Kee, Bryan K., Kanwal Pratap Singh, Raghav, Manuel, Shanequa, Shureiqi, Imad, Wolff, Robert A., Eng, Cathy, Menter, David, Hamilton, Stanley R., Kopetz, Scott, Dasari, Arvind
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2017
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503612/
https://ncbi.nlm.nih.gov/pubmed/28424412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16848
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料