Association of SMAD4 mutation with patient demographics, tumor characteristics, and clinical outcomes in colorectal cancer

SMAD4 is an essential mediator in the transforming growth factor-β pathway. Sporadic mutations of SMAD4 are present in 2.1–20.0% of colorectal cancers (CRCs) but data are limited. In this study, we aimed to evaluate clinicopathologic characteristics, prognosis, and clinical outcome associated with t...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:PLoS One
Päätekijät: Sarshekeh, Amir Mehrvarz, Advani, Shailesh, Overman, Michael J., Manyam, Ganiraju, Kee, Bryan K., Fogelman, David R., Dasari, Arvind, Raghav, Kanwal, Vilar, Eduardo, Manuel, Shanequa, Shureiqi, Imad, Wolff, Robert A., Patel, Keyur P., Luthra, Raja, Shaw, Kenna, Eng, Cathy, Maru, Dipen M., Routbort, Mark J., Meric-Bernstam, Funda, Kopetz, Scott
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2017
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5340382/
https://ncbi.nlm.nih.gov/pubmed/28267766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0173345
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