Classifying colorectal cancer by tumor location rather than sidedness highlights a continuum in mutation profiles and Consensus Molecular Subtypes

PURPOSE: Colorectal cancers (CRCs) are classified as right/left sided based on whether they occur before/after the splenic flexure, with established differences in molecular subtypes and outcomes. However, it is unclear if this division is optimal and whether precise tumor location provides further...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Loree, Jonathan M., Pereira, Allan A.L., Lam, Michael, Willauer, Alexandra N., Raghav, Kanwal, Dasari, Arvind, Morris, Van. K, Advani, Shailesh, Menter, David G., Eng, Cathy, Shaw, Kenna, Broaddus, Russell, Routbort, Mark J., Liu, Yusha, Morris, Jeffrey S., Luthra, Rajyalakshmi, Meric-Bernstam, Funda, Overman, Michael J., Maru, Dipen, Kopetz, Scott
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5844818/
https://ncbi.nlm.nih.gov/pubmed/29180604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2484
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