Mutation of a nucleosome compaction region disrupts Polycomb-mediated axial patterning

Nucleosomes play important structural and regulatory roles by tightly wrapping the DNA that constitutes the metazoan genome. The Polycomb group (PcG) proteins modulate nucleosomes to maintain repression of key developmental genes, including Hox genes whose temporal and spatial expression is tightly...

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Detaylı Bibliyografya
Yayımlandı:Science
Asıl Yazarlar: Lau, Mei Sheng, Schwartz, Matthew G., Kundu, Sharmistha, Savol, Andrej J., Wang, Peggy I., Marr, Sharon K., Grau, Daniel J., Schorderet, Patrick, Sadreyev, Ruslan I., Tabin, Clifford J., Kingston, Robert E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5503153/
https://ncbi.nlm.nih.gov/pubmed/28280206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aah5403
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