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Polycomb Repressive Complex 1 generates discrete compacted domains that change during differentiation

Master regulatory genes require stable silencing by the Polycomb-Group (PcG) to prevent misexpression during differentiation and development. Some PcG proteins covalently modify histones, which contributes to heritable repression. The role for other effects on chromatin structure is less understood....

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Bibliografiska uppgifter
I publikationen:Mol Cell
Huvudupphovsmän: Kundu, Sharmistha, Ji, Fei, Sunwoo, Hongjae, Jain, Gaurav, Lee, Jeannie T., Sadreyev, Ruslan I., Dekker, Job, Kingston, Robert E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421375/
https://ncbi.nlm.nih.gov/pubmed/28157505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.009
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