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Polycomb Repressive Complex 1 generates discrete compacted domains that change during differentiation
Master regulatory genes require stable silencing by the Polycomb-Group (PcG) to prevent misexpression during differentiation and development. Some PcG proteins covalently modify histones, which contributes to heritable repression. The role for other effects on chromatin structure is less understood....
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| Udgivet i: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5421375/ https://ncbi.nlm.nih.gov/pubmed/28157505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.009 |
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