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Polycomb Repressive Complex 1 generates discrete compacted domains that change during differentiation

Master regulatory genes require stable silencing by the Polycomb-Group (PcG) to prevent misexpression during differentiation and development. Some PcG proteins covalently modify histones, which contributes to heritable repression. The role for other effects on chromatin structure is less understood....

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Kundu, Sharmistha, Ji, Fei, Sunwoo, Hongjae, Jain, Gaurav, Lee, Jeannie T., Sadreyev, Ruslan I., Dekker, Job, Kingston, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5421375/
https://ncbi.nlm.nih.gov/pubmed/28157505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.01.009
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