Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro

The negatively charged nonulose sialic acid (Sia) is essential for murine development in vivo. In order to elucidate the impact of sialylation on differentiation processes in the absence of maternal influences, we generated mouse embryonic stem cell (mESC) lines that lack CMP‐Sia synthetase (CMAS) a...

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Bibliografske podrobnosti
izdano v:Chembiochem
Main Authors: Abeln, Markus, Borst, Kristina M., Cajic, Samanta, Thiesler, Hauke, Kats, Elina, Albers, Iris, Kuhn, Maike, Kaever, Volkhard, Rapp, Erdmann, Münster‐Kühnel, Anja, Weinhold, Birgit
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Full Papers
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502888/
https://ncbi.nlm.nih.gov/pubmed/28374933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700083
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