Sialylation Is Dispensable for Early Murine Embryonic Development in Vitro

The negatively charged nonulose sialic acid (Sia) is essential for murine development in vivo. In order to elucidate the impact of sialylation on differentiation processes in the absence of maternal influences, we generated mouse embryonic stem cell (mESC) lines that lack CMP‐Sia synthetase (CMAS) a...

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Published in:Chembiochem
Main Authors: Abeln, Markus, Borst, Kristina M., Cajic, Samanta, Thiesler, Hauke, Kats, Elina, Albers, Iris, Kuhn, Maike, Kaever, Volkhard, Rapp, Erdmann, Münster‐Kühnel, Anja, Weinhold, Birgit
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502888/
https://ncbi.nlm.nih.gov/pubmed/28374933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201700083
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