Deficits in Sialylation Impair Podocyte Maturation

The role of sialylation in kidney biology is not fully understood. The synthesis of sialoglycoconjugates, which form the outermost structures of animal cells, requires CMP-sialic acid, which is a product of the nuclear enzyme CMAS. We used a knock-in strategy to create a mouse with point mutations i...

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Detalhes bibliográficos
Main Authors: Weinhold, Birgit, Sellmeier, Melanie, Schaper, Wiebke, Blume, Linda, Philippens, Brigitte, Kats, Elina, Bernard, Ulrike, Galuska, Sebastian P., Geyer, Hildegard, Geyer, Rudolf, Worthmann, Kirstin, Schiffer, Mario, Groos, Stephanie, Gerardy-Schahn, Rita, Münster-Kühnel, Anja K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2012
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402283/
https://ncbi.nlm.nih.gov/pubmed/22745475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2011090947
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