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Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease

Polycystic kidney diseases (PKDs) are genetic disorders that can cause renal failure and death in children and adults. Lowering cAMP in cystic tissues through the inhibition of the type-2 vasopressin receptor (V2R) constitutes a validated strategy to reduce disease progression. We identified a pepti...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Ciolek, Justyna, Reinfrank, Helen, Quinton, Loïc, Viengchareun, Say, Stura, Enrico A., Vera, Laura, Sigismeau, Sabrina, Mouillac, Bernard, Orcel, Hélène, Peigneur, Steve, Tytgat, Jan, Droctové, Laura, Beau, Fabrice, Nevoux, Jerome, Lombès, Marc, Mourier, Gilles, De Pauw, Edwin, Servent, Denis, Mendre, Christiane, Witzgall, Ralph, Gilles, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502595/
https://ncbi.nlm.nih.gov/pubmed/28630289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620454114
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