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Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease
Polycystic kidney diseases (PKDs) are genetic disorders that can cause renal failure and death in children and adults. Lowering cAMP in cystic tissues through the inhibition of the type-2 vasopressin receptor (V2R) constitutes a validated strategy to reduce disease progression. We identified a pepti...
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Publicado no: | Proc Natl Acad Sci U S A |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5502595/ https://ncbi.nlm.nih.gov/pubmed/28630289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1620454114 |
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