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Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins
Mamba venoms contain a multiplicity of three-finger fold aminergic toxins known to interact with various α-adrenergic, muscarinic and dopaminergic receptors with different pharmacological profiles. In order to generate novel functions on this structural scaffold and to avoid the daunting task of pro...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5457417/ https://ncbi.nlm.nih.gov/pubmed/28578406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02953-0 |
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