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Systemic delivery of HK Raf-1 siRNA Polyplexes Inhibits MDA-MB-435 Xenografts

Our past research has focused on identifying an effective carrier composed of histidine and lysine for delivery of nucleic acid into cells. For this purpose, we developed histidine-lysine-rich (HK) polymers with specific sequences and branching. We have found that branched HK polymers in complex wit...

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Publicat a:Cancer Gene Ther
Autors principals: Leng, Qixin, Scaria, Puthupparampil, Lu, Patrick, Woodle, MC, Mixson, A. James
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5502125/
https://ncbi.nlm.nih.gov/pubmed/18483501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2008.29
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