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Buffering Capacity and Size of siRNA Polyplexes Influence Cytokine Levels
Induction of cytokines by small interfering RNA (siRNA) polyplexes has been a significant concern of researchers attempting to minimize the toxicity of this promising therapy. Although cationic carriers of siRNA are known to increase cytokine levels, few systematic studies have been done to determin...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3519993/ https://ncbi.nlm.nih.gov/pubmed/23032972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.206 |
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