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Selective Modification of HK Peptides Enhances siRNA Silencing of Tumor Targets In Vivo
Our research has focused on systemic delivery of small interference RNA (siRNA) by branched peptides composed of histidine and lysine, called HK peptides. After studying several HK peptides, one four-branched peptide, H3K(+H)4b, with a predominant repeating pattern of -HHHK-, was found to be an effe...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177007/ https://ncbi.nlm.nih.gov/pubmed/21818135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2011.40 |
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