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Advances in Systemic siRNA Delivery

Sequence-specific gene silencing with small interfering RNA (siRNA) has transformed basic science research, and the efficacy of siRNA therapeutics toward a variety of diseases is now being evaluated in pre-clinical and clinical trials. Despite its potential value, the highly negatively charged siRNA...

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Detalhes bibliográficos
Main Authors: Leng, Qixin, Woodle, Martin C, Lu, Patrick Y, Mixson, A James
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812054/
https://ncbi.nlm.nih.gov/pubmed/20161621
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