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Harnessing in vivo siRNA delivery for drug discovery and therapeutic development

The use of RNA interference (RNAi) is spreading rapidly to nearly every aspect of biomedical research. The gene silencing capability of RNAi is being used to study individual gene's biological function and role in biochemical pathways. However, the efficacy of RNAi depends upon efficient delive...

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Publicat a:Drug Discov Today
Autors principals: Xie, Frank Y., Woodle, Martin C., Lu, Patrick Y.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Ltd. 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7108327/
https://ncbi.nlm.nih.gov/pubmed/16478693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S1359-6446(05)03668-8
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