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A FAK-YAP-mTOR signaling axis regulates stem cell-based tissue renewal in mice
Tissue homeostasis requires production of newly differentiated cells from resident adult stem cells. Central to this process is the expansion of undifferentiated intermediates known as transit-amplifying (TA) cells, but how stem cells are triggered to enter this proliferative TA state remains an imp...
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| 出版年: | Cell Stem Cell |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501749/ https://ncbi.nlm.nih.gov/pubmed/28457749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.03.023 |
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