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A FAK-YAP-mTOR signaling axis regulates stem cell-based tissue renewal in mice
Tissue homeostasis requires production of newly differentiated cells from resident adult stem cells. Central to this process is the expansion of undifferentiated intermediates known as transit-amplifying (TA) cells, but how stem cells are triggered to enter this proliferative TA state remains an imp...
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| 發表在: | Cell Stem Cell |
|---|---|
| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5501749/ https://ncbi.nlm.nih.gov/pubmed/28457749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2017.03.023 |
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