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Leishmania donovani resides in modified early endosomes by upregulating Rab5a expression via the downregulation of miR-494

Several intracellular pathogens arrest the phagosome maturation in the host cells to avoid transport to lysosomes. In contrast, the Leishmania containing parasitophorous vacuole (PV) is shown to recruit lysosomal markers and thus Leishmania is postulated to be residing in the phagolysosomes in macro...

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Detalles Bibliográficos
Publicado en:PLoS Pathog
Main Authors: Verma, Jitender Kumar, Rastogi, Ruchir, Mukhopadhyay, Amitabha
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501680/
https://ncbi.nlm.nih.gov/pubmed/28650977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006459
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