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Compound 331 selectively induces glioma cell death by upregulating miR-494 and downregulating CDC20

Malignant gliomas are the most common malignant tumors in the central nervous system (CNS). Up to date, the prognosis of glioma is still very poor, effective therapy with less side-effect is very necessary. Herein, we identify a compound named as “331” selectively induced cell death in glioma cells...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Lei, Niu, Tianhui, Huang, Yafei, Zhu, Haichuan, Zhong, Wu, Lin, Jian, Zhang, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4495416/
https://ncbi.nlm.nih.gov/pubmed/26153143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12003
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