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Assessment of circulating copy number variant detection for cancer screening

Current high-sensitivity cancer screening methods, largely utilizing correlative biomarkers, suffer from false positive rates that lead to unnecessary medical procedures and debatable public health benefit overall. Detection of circulating tumor DNA (ctDNA), a causal biomarker, has the potential to...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Molparia, Bhuvan, Nichani, Eshaan, Torkamani, Ali
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501586/
https://ncbi.nlm.nih.gov/pubmed/28686671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180647
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