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Assessment of circulating copy number variant detection for cancer screening

Current high-sensitivity cancer screening methods, largely utilizing correlative biomarkers, suffer from false positive rates that lead to unnecessary medical procedures and debatable public health benefit overall. Detection of circulating tumor DNA (ctDNA), a causal biomarker, has the potential to...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Molparia, Bhuvan, Nichani, Eshaan, Torkamani, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501586/
https://ncbi.nlm.nih.gov/pubmed/28686671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180647
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