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Assessment of circulating copy number variant detection for cancer screening

Current high-sensitivity cancer screening methods, largely utilizing correlative biomarkers, suffer from false positive rates that lead to unnecessary medical procedures and debatable public health benefit overall. Detection of circulating tumor DNA (ctDNA), a causal biomarker, has the potential to...

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Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Molparia, Bhuvan, Nichani, Eshaan, Torkamani, Ali
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501586/
https://ncbi.nlm.nih.gov/pubmed/28686671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180647
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