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Orphan CpG islands define a novel class of highly active enhancers

CpG islands (CGI) are critical genomic regulatory elements that support transcriptional initiation and are associated with the promoters of most human genes. CGI are distinguished from the bulk genome by their high CpG density, lack of DNA methylation, and euchromatic features. While CGI are canonic...

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Bibliografski detalji
Izdano u:Epigenetics
Glavni autori: Bell, Joshua S. K., Vertino, Paula M.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5501197/
https://ncbi.nlm.nih.gov/pubmed/28448736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2017.1297910
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