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In Vitro Transport Activity and Trafficking of MRP2/ABCC2 Polymorphic Variants
PURPOSE: Multidrug resistance-associated protein 2 (MRP2/ABCC2) is an efflux pump that removes drugs and chemicals from cells. We sought to characterize the expression, trafficking and in vitro activity of seven single nucleotide polymorphisms (SNPs) in the ABCC2 gene. METHODS: ABCC2 SNPs were gener...
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| Published in: | Pharm Res |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5500460/ https://ncbi.nlm.nih.gov/pubmed/28405913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2160-0 |
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