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A platform for functional assessment of large variant libraries in mammalian cells

Sequencing-based, massively parallel genetic assays have revolutionized our ability to quantify the relationship between many genotypes and a phenotype of interest. Unfortunately, variant library expression platforms in mammalian cells are far from ideal, hindering the study of human gene variants i...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Matreyek, Kenneth A., Stephany, Jason J., Fowler, Douglas M.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499817/
https://ncbi.nlm.nih.gov/pubmed/28335006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx183
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