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Targeted ‘knockdown’ of spliceosome function in mammalian cells

The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions—ranging from their impact on proteome expansion to the evolution of splicing and of metazoan genomes. Exploring roles for the distinct splicing systems in vivo has, however, be...

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Bibliographic Details
Main Authors: Matter, Nathalie, König, Harald
Format: Artigo
Language:Inglês
Published: Oxford University Press 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC549580/
https://ncbi.nlm.nih.gov/pubmed/15731334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni041
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