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Targeted ‘knockdown’ of spliceosome function in mammalian cells

The existence of two sophisticated parallel splicing machineries in multicellular organisms has raised intriguing questions—ranging from their impact on proteome expansion to the evolution of splicing and of metazoan genomes. Exploring roles for the distinct splicing systems in vivo has, however, be...

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Autors principals: Matter, Nathalie, König, Harald
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC549580/
https://ncbi.nlm.nih.gov/pubmed/15731334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gni041
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