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The Impact of Genetic Variants on PTEN Molecular Functions and Cellular Phenotypes

Phosphatase and tensin homolog (PTEN) is a tumor suppressor that directly regulates a diverse array of cellular phenotypes, including growth, migration, morphology, and genome stability. How a single protein impacts so many important cellular processes remains a fascinating question. This question h...

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Bibliografiske detaljer
Udgivet i:Cold Spring Harb Perspect Med
Main Authors: Hasle, Nicholas, Matreyek, Kenneth A., Fowler, Douglas M.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824405/
https://ncbi.nlm.nih.gov/pubmed/31451538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a036228
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