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Human DDX21 binds and unwinds RNA guanine quadruplexes

Guanine quadruplexes (G4s) are an important structure of nucleic acids (DNA and RNA) with roles in several cellular processes. RNA G4s require specialized unwinding enzymes, of which only two have been previously identified. We describe the results of a simple and specific mass spectrometry guided m...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: McRae, Ewan K.S., Booy, Evan P., Moya-Torres, Aniel, Ezzati, Peyman, Stetefeld, Jörg, McKenna, Sean A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499804/
https://ncbi.nlm.nih.gov/pubmed/28472472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx380
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