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An RNA guanine quadruplex regulated pathway to TRAIL-sensitization by DDX21

DDX21 is a newly discovered RNA G-quadruplex (rG4) binding protein with no known biological rG4 targets. In this study we used label-free proteomic MS/MS to identify 26 proteins that are expressed at significantly different levels in cells expressing an rG4-binding deficient DDX21 (M4). MS data are...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: McRae, Ewan K.S., Dupas, Steven J., Booy, Evan P., Piragasam, Ramanaguru S., Fahlman, Richard P., McKenna, Sean A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6913123/
https://ncbi.nlm.nih.gov/pubmed/31653714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.072199.119
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