Human DDX21 binds and unwinds RNA guanine quadruplexes

Guanine quadruplexes (G4s) are an important structure of nucleic acids (DNA and RNA) with roles in several cellular processes. RNA G4s require specialized unwinding enzymes, of which only two have been previously identified. We describe the results of a simple and specific mass spectrometry guided m...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: McRae, Ewan K.S., Booy, Evan P., Moya-Torres, Aniel, Ezzati, Peyman, Stetefeld, Jörg, McKenna, Sean A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Nucleic Acid Enzymes
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499804/
https://ncbi.nlm.nih.gov/pubmed/28472472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx380
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