Human DDX21 binds and unwinds RNA guanine quadruplexes

Guanine quadruplexes (G4s) are an important structure of nucleic acids (DNA and RNA) with roles in several cellular processes. RNA G4s require specialized unwinding enzymes, of which only two have been previously identified. We describe the results of a simple and specific mass spectrometry guided m...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: McRae, Ewan K.S., Booy, Evan P., Moya-Torres, Aniel, Ezzati, Peyman, Stetefeld, Jörg, McKenna, Sean A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Nucleic Acid Enzymes
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499804/
https://ncbi.nlm.nih.gov/pubmed/28472472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx380
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