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Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination

Histone H2B lysine 120 mono-ubiquitination (H2Bub1) catalyzed by Rnf20 has been implicated in normal differentiation of embryonic stem (ES) and adult stem cells. However, it remains unknown how Rnf20 is recruited to its specific target chromosomal loci for the establishment of H2Bub1. Here, we revea...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Lee, Bum-Kyu, Lee, Jiwoon, Shen, Wenwen, Rhee, Catherine, Chung, Haewon, Kim, Jonghwan
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499583/
https://ncbi.nlm.nih.gov/pubmed/28453857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx310
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