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Fbxl19 recruitment to CpG islands is required for Rnf20-mediated H2B mono-ubiquitination

Histone H2B lysine 120 mono-ubiquitination (H2Bub1) catalyzed by Rnf20 has been implicated in normal differentiation of embryonic stem (ES) and adult stem cells. However, it remains unknown how Rnf20 is recruited to its specific target chromosomal loci for the establishment of H2Bub1. Here, we revea...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Lee, Bum-Kyu, Lee, Jiwoon, Shen, Wenwen, Rhee, Catherine, Chung, Haewon, Kim, Jonghwan
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499583/
https://ncbi.nlm.nih.gov/pubmed/28453857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx310
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