Islet inflammation and ductal proliferation may be linked to increased pancreatitis risk in type 2 diabetes

Pancreatitis is more frequent in type 2 diabetes mellitus (T2DM), although the underlying cause is unknown. We tested the hypothesis that ongoing β cell stress and apoptosis in T2DM induces ductal tree proliferation, particularly the pancreatic duct gland (PDG) compartment, and thus potentially obst...

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Publicat a:JCI Insight
Autors principals: Schludi, Belinda, Moin, Abu Saleh Md, Montemurro, Chiara, Gurlo, Tatyana, Matveyenko, Aleksey V., Kirakossian, David, Dawson, David W., Dry, Sarah M., Butler, Peter C., Butler, Alexandra E.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499368/
https://ncbi.nlm.nih.gov/pubmed/28679961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92282
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