Beneficial Endocrine but Adverse Exocrine Effects of Sitagliptin in the Human Islet Amyloid Polypeptide Transgenic Rat Model of Type 2 Diabetes: Interactions With Metformin

OBJECTIVE: We sought to establish the extent and mechanisms by which sitagliptin and metformin singly and in combination modify islet disease progression in human islet amyloid polypeptide transgenic (HIP) rats, a model for type 2 diabetes. RESEARCH DESIGN AND METHODS: HIP rats were treated with sit...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Matveyenko, Aleksey V., Dry, Sarah, Cox, Heather I., Moshtaghian, Artemis, Gurlo, Tatyana, Galasso, Ryan, Butler, Alexandra E., Butler, Peter C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2009
Soggetti:
Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699878/
https://ncbi.nlm.nih.gov/pubmed/19403868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0058
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi