Islet inflammation and ductal proliferation may be linked to increased pancreatitis risk in type 2 diabetes

Pancreatitis is more frequent in type 2 diabetes mellitus (T2DM), although the underlying cause is unknown. We tested the hypothesis that ongoing β cell stress and apoptosis in T2DM induces ductal tree proliferation, particularly the pancreatic duct gland (PDG) compartment, and thus potentially obst...

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Foilsithe in:JCI Insight
Main Authors: Schludi, Belinda, Moin, Abu Saleh Md, Montemurro, Chiara, Gurlo, Tatyana, Matveyenko, Aleksey V., Kirakossian, David, Dawson, David W., Dry, Sarah M., Butler, Peter C., Butler, Alexandra E.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2017
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5499368/
https://ncbi.nlm.nih.gov/pubmed/28679961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92282
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