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CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer

BACKGROUND: DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ALKBH2 and ALKBH3 have also been linked to direct...

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Bibliografski detalji
Izdano u:BMC Cancer
Glavni autori: Stefansson, Olafur Andri, Hermanowicz, Stefan, van der Horst, Jasper, Hilmarsdottir, Holmfridur, Staszczak, Zuzanna, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Gudjonsson, Thorkell, Sigurdsson, Stefan
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498885/
https://ncbi.nlm.nih.gov/pubmed/28679371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3453-8
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