CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer

BACKGROUND: DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ALKBH2 and ALKBH3 have also been linked to direct...

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Udgivet i:BMC Cancer
Main Authors: Stefansson, Olafur Andri, Hermanowicz, Stefan, van der Horst, Jasper, Hilmarsdottir, Holmfridur, Staszczak, Zuzanna, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Gudjonsson, Thorkell, Sigurdsson, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498885/
https://ncbi.nlm.nih.gov/pubmed/28679371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3453-8
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