CpG promoter methylation of the ALKBH3 alkylation repair gene in breast cancer

BACKGROUND: DNA repair of alkylation damage is defective in various cancers. This occurs through somatically acquired inactivation of the MGMT gene in various cancer types, including breast cancers. In addition to MGMT, the two E. coli AlkB homologs ALKBH2 and ALKBH3 have also been linked to direct...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Stefansson, Olafur Andri, Hermanowicz, Stefan, van der Horst, Jasper, Hilmarsdottir, Holmfridur, Staszczak, Zuzanna, Jonasson, Jon Gunnlaugur, Tryggvadottir, Laufey, Gudjonsson, Thorkell, Sigurdsson, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498885/
https://ncbi.nlm.nih.gov/pubmed/28679371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3453-8
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