Altered mechanisms of protein synthesis in frontal cortex in Alzheimer disease and a mouse model

Expression of the nucleolar chaperones nucleolin (NCL) and nucleophosmin (NPM1), upstream binding transcription factor (UBTF), rRNA18S, rRNA28S, and several genes encoding ribosomal proteins (RPs) is decreased in frontal cortex area 8 at advanced stages of Alzheimer’s disease (AD). This is accompani...

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Dettagli Bibliografici
Pubblicato in:Am J Neurodegener Dis
Autori principali: Garcia-Esparcia, Paula, Sideris-Lampretsas, Georgios, Hernandez-Ortega, Karina, Grau-Rivera, Oriol, Sklaviadis, Theodoros, Gelpi, Ellen, Ferrer, Isidro
Natura: Artigo
Lingua:Inglês
Pubblicazione: e-Century Publishing Corporation 2017
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498849/
https://ncbi.nlm.nih.gov/pubmed/28695061
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